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Lifeasible Enhances Yeast-Based Screening Platform to Accelerate Plant Resistance Research

By Editorial Staff

TL;DR

Lifeasible's updated yeast-based screening platform gives researchers a competitive edge by rapidly identifying plant resistance genes to develop hardier, higher-yielding crops more efficiently.

Lifeasible's platform works by constructing yeast expression libraries from plant RNA, then screening clones under adverse conditions to identify and validate resistance genes through protein expression.

This technology helps create more resilient crops that can withstand environmental stresses, potentially improving food security and reducing agriculture's environmental impact for a better tomorrow.

Lifeasible uses yeast as a model organism to screen plant genes, offering a faster, more cost-effective alternative to traditional methods for discovering how plants resist toxins.

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Lifeasible Enhances Yeast-Based Screening Platform to Accelerate Plant Resistance Research

Lifeasible, a biotechnology company specializing in agricultural research, has announced an update to its yeast-based high-throughput screening platform designed to help researchers rapidly identify plant genes that confer resistance to environmental stressors, pests, pathogens, and heavy metals. This development comes as plants face increasing challenges from persistent heavy metal contamination in soil, disease attacks, and other environmental stresses that significantly affect plant growth, yield, and crop quality.

The identification of genes associated with resistance is crucial for modern breeding programs, yet traditional screening methods are often slow, time-consuming, and have limited throughput. Lifeasible's updated platform addresses these limitations by offering faster and more cost-effective methods. The company notes that in toxicology and stress response studies, model systems such as yeast provide a viable alternative to animal models, enabling high-throughput gene function analysis at a lower cost.

Backed by years of experience in molecular biology, Lifeasible now offers one-stop services for high-throughput resistance gene screening using yeast. These services include construction of yeast expression libraries, isolation of RNA, construction of cDNA libraries, high-throughput screening for resistance genes, preparation of yeast working solutions, exploration of appropriate adverse conditions, screening of positive yeast clones under adverse conditions, gene identification of yeast positive clones, protein-induced expression and validation, phenotypic validation of yeast, knock out yeast strain creation and transformation, and complement verification through overexpression.

"We are excited about the update of our yeast-based high-throughput screening platform. By combining the speed and flexibility of yeast genetics with a robust screening workflow, we are sure scientists will explore complex resistance mechanisms more efficiently, thus unlocking new possibilities in plant biotechnology and crop improvement," commented Isla, a representative speaker from Lifeasible.

For business and technology leaders in agriculture and biotechnology, this advancement represents a significant step toward more resilient food systems. The ability to rapidly identify resistance genes could accelerate the development of crops that withstand climate-related stresses, reduce pesticide dependency, and improve yields in contaminated soils. This has implications for global food security, sustainable agriculture practices, and the economic stability of farming communities worldwide.

The platform update aligns with growing industry demands for precision breeding tools that can keep pace with evolving environmental challenges. Over the years, Lifeasible has provided a wide range of services in plant biotechnology, including gene cloning, gene expression, modification, protein-protein or protein-DNA interactions, cell imaging, and phytochemical analysis to meet diversified research needs. Researchers seeking detailed information about the updated yeast-based high-throughput screening for resistance genes can visit https://www.lifeasible.com/custom-solutions/plant/analytical-services/high-throughput-screening-for-resistance-genes-using-yeast/.

Curated from 24-7 Press Release

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Editorial Staff

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