Lionheart Health, Inc. has announced that enrollment is beginning for its Lionheart Klotho-Up™ Study, a longitudinal program designed to assess whether a practical, structured wellness and bioelectric intervention program may help support key markers of healthy aging. The study is built around two core required elements: daily Klotho-favoring meals, supplements, and beverages, and BodStim™ Klotho-enhancing exercise performed two or three times per week. Participants may also choose from optional supportive therapies, which could include hyperbaric oxygen therapy, red light therapy, cold therapy, pulsed electromagnetic field (PEMF) therapy, and organ-targeted bioelectric stimulation, depending on availability and site offerings.
Howard Leonhardt, Executive Chairman and co-CEO of Lionheart Health, stated the company's goal is to make a Klotho-supportive lifestyle and bioelectric wellness program more structured, measurable, and accessible. The study aims to provide participants with a guided program, objective testing, and the opportunity to track whether their efforts are improving meaningful indicators of muscle, cognitive, and immune health over time. All participants must complete a formal informed patient consent process and agree to required baseline and one-year follow-up assessments, which include muscle health tests like grip strength and gait speed, brain health evaluations through standardized cognitive testing, and immune health assessments via gut intelligence testing and various biomarkers.
A central component of the study is a 461 blood biomarker panel conducted at baseline and again at one year, with optional testing at three and six months. An AI-enhanced MRI through https://www.CoreViva.com will also be available optionally for deeper body composition insights. The study focuses on Klotho, a longevity-associated protein linked to healthy muscle function, brain health, vascular and metabolic health, inflammation balance, and overall healthy aging biology. Many individuals seek to support Klotho-related biology to maintain strength, mobility, energy, cognitive sharpness, and immune resilience with age.
Enrollment is opening on a limited basis for qualified participants at licensed clinic locations as a subsidized paid registry study. Participants will pay $12.99 per day for Klotho-favoring meals delivered to their home or can prepare their own meals following provided recipes at a lower cost. The BodStim™ EMS suit can be leased for one year with an $890 down payment and monthly payments of $188. The 461 biomarker test costs $800 each for non-members and $463 for members. Lionheart Health will cover all required muscle, brain, and immunity health test assessments at baseline and one year, while participants cover costs for optional additional tests and optional AI-enhanced MRI scans.
This study supports Lionheart Health's participation in XPRIZE Healthspan, where the company was named a Top 40 Milestone 1 awardee semi-finalist from more than 600 registered teams worldwide. For more information about the study, eligibility, participating sites, and informed consent requirements, visit https://www.LionheartLongevity.com. The Lionheart Klotho-Up™ Study is intended for research, wellness, and health optimization purposes, with participation requiring informed consent and individual results potentially varying.
